21 Fifty Pitches Way
Cardonald Business Park
Glasgow, G51 4FD

0141 - 891 - 8749
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Treatments available for the subfertile couple

The GCRM has been set up to provide treatments which the NHS does not currently provide and also to provide conventional treatments for couples to whom NHS treatment is denied.

In vitro fertilisation (IVF)
A Blastocyst IVF was developed for women where there is a Fallopian tube problem. It involves the woman having daily injections of follicle stimulating hormone (FSH or human menopausal gonadotrophins, HMG) for around 12 days, which stimulates eggs to grow. Most women give themselves the injections or get their partner to do it. The response to these injections is monitored, and at the appropriate time, the eggs (oocytes) are collected from the ovaries with a needle, in a procedure that usually takes around half an hour, during which you are sedated. The eggs are then mixed with your partner’s sperm, fertilsation occurs and embryos are produced. Usually one or two embryos are put back in the womb, two or three days later. For further information please click HERE.

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Intracytoplasmic Sperm Injection (ICSI)
ICSI was developed for couples where there is a problem with the numbers of sperm. The woman goes through the same process as for IVF but a single sperm is injected directly into the egg (rather than allowing them to try and fuse naturally). In these circumstances, ICSI improves the chances of fertilisation, and hence increases the chances of having embryos to put back in the womb. For further information please click HERE.

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Surgical Sperm Retrieval
If the tube which connects each testicle to the penis (the vas deferens) is blocked, sperm cannot get out with the ejaculate. However, sperm can be recovered directly from the testicle using techniques called MESA (micro-surgical sperm aspiration), TESA ( testicular sperm aspiration) or PESA ( percutaneous epididymal sperm aspiration) undertaken by a urologist. For further information please click HERE.

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Intrauterine insemination (IUI)
In cases of unexplained infertility, where the woman has been shown to be ovulating normally or where a couple might have difficulty having intercourse, the partner’s sperm is prepared and inseminated in to the womb at the time of ovulation without the need for stimulatory drugs.

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Ovulation induction and intrauterine insemination (OI/IUI)
The woman goes through the same injections as for IVF (but uses lower doses of FSH or HMG) and at the appropriate time her partner’s sperm is prepared and inseminated into the womb. Cycle for cycle, OI/IUI is not as successful as IVF but it is considerably less expensive and in cases of unexplained infertility, OI/IUI might be appropriate.

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Blastocyst culture
A Blastocyst A blastocyst is an embryo that has been allowed to develop in the laboratory for five days or more after egg collection, during which time it grows into a bundle of cells. In standard IVF, embryos are allowed to develop for only two or three days in the laboratory before being transferred into the uterus. There is evidence supporting the use of blastocyst culture and transfer in certain patients. One such group are those where there are a number of similar embryos on day 2 or 3, and it is difficult to distinguish which are the best. Published figures show that of all embryos replaced in the uterus on day 2 or 3, only 15-20% actually implant and become a pregnancy, while in some patients, blastocysts are up to twice as likely to implant. There are a number of possible reasons for this improved success rate, but the most likely is that embryos which develop successfully to blastocyst stage are growing better than the others, and have a higher potential to implant.

So if it is so successful why is blastocyst transfer not used for everyone?

The problem is that many embryos do not survive five days in the laboratory, and if not carefully selected, some patients would not get an embryo transfer.

At the GCRM, as a guide, patients with at least 4 good quality embryos on day 3 will be considered suitable for blastocyst stage transfer. If the number of embryos is lower there will be no advantage to leaving the embryos outside the uterus, as we already know which embryos are best selected for transfer. It must be emphasised that this policy does not compromise the success rate of patients who do not proceed to the blastocyst stage - most IVF pregnancies still follow day 2 or 3 transfers.

The cost of IVF or ICSI treatment at the GCRM is fully inclusive of all costs associated with blastocyst culture and transfer.

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Embryo freezing
Embryo freezing is now a well established procedure. It allows us to freeze any good quality embryos that remain after embryo transfer. Due to the high implantation rates with both fresh blastocyst transfer and those frozen and thawed, GCRM will normally freeze remaining embryos at the blastocyst stage. This means that any extra good quality embryos following a blastocyst transfer will be frozen. All embryos remaining after a Day 2 or 3 transfer will be assessed, and if suitable, will be cultured to Day 5 with any suitable quality blastocysts being frozen.

The cost of IVF or ICSI treatment at the GCRM is fully inclusive of Embryo freezing and the first years storage.

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Sperm freezing
Like embryo freezing, sperm freezing is now well established. There are a variety of reasons why sperm may need to be stored including:

  • Prior to chemo or radiotherapy
  • Prior to vasectomy
  • Prior to any surgery that may result in impaired fertility
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For further information on Embryo/Sperm freezing or any of the other treatment options above please Contact GCRM.